دانلود مقاله Analytical Study on the Turbaulent shearدرinduced hemolysis and platelet activation downstream of mechanical heart
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سال انتشار: 1390
محل انتشار: هجدهمین کنفرانس مهندسی پزشکی ایران
تعداد صفحات: 5
نویسنده(ها):
A Omidvar – Department of Mechanical and Aerospace Enginnering Shiraz University of Technology, Shiraz
E Amini – Shiraz University of Medical Science, Shiraz, Iran
چکیده:
Mechanical heart valves (MHVs) are widely implanted to replace the diseased heart valves. The performance of these valves strongly is limited by complications such as hemolysis and platelet activation. Abnormal flow patterns and turbulence generated by MHVs are the major reasons of these problems. Thus a better understanding of MHV hemodynamics is very important. In the present study, a simplified analytical approach is proposed to predict turbulent shear-induced hemolysis and platelet activation downstream of mechanical hear valves. This theoretical model was validated with such available in vivo experimental results where a good agreement was found. Therefore the present model provides a new insight into the behavior of turbulent Reynolds stresses downstream of the various mechanical heart valves and estimates them accurately without any extra computational or experimental cost.